In short: The main travel hubs are at moderate altitude: Guatemala City about 1,510 m, Antigua about 1,580 m, the Lake Atitlán towns about 1,580-1,690 m. Quetzaltenango (Xela) is about 2,350 m, and Totonicapán and Todos Santos Cuchumatán about 2,500 m. The CDC Yellow Book puts the line at a sleeping altitude of 2,450 m (8,000 ft): above it, any unacclimatized traveller is at risk of altitude illness, and sometimes lower. What crosses it: the volcano summits (Acatenango 3,976 m, Tajumulco 4,220 m, Santa María 3,772 m and others), especially on trips that camp on the mountain, and the highest highland towns. Tikal, Flores, Lanquín, Río Dulce and the Pacific beaches are low.

This page gives one number per place and sets it against the CDC’s thresholds. It is not medical advice and does not cover medication or dosing: for that, see a doctor or travel clinic. For the hikes themselves, see our Acatenango and Tajumulco guides.

The CDC lines that matter

All from the CDC Yellow Book chapter High-Altitude Travel and Altitude Illness (read 25 September 2026):

CDC thresholdWhat the CDC says
2,450 m (8,000 ft) sleeping altitudeAny unacclimatized traveller sleeping at or above this height, “and sometimes lower”, is at risk for altitude illness.
2,750 m (9,000 ft) in one dayAvoid going directly from low altitude (below 1,200 m / 4,000 ft) to a sleeping altitude above 2,750 m in one day.
Above 3,000 m (9,850 ft)Move sleeping altitude by no more than 500 m (1,600 ft) per day, with an extra day of acclimatization for every additional 1,000 m.
Day tripsDay trips to high altitude with an evening return to a lower altitude are much less stressful on the body.
DescentAcute mountain sickness improves rapidly with a descent of 300 m (1,000 ft) or more.
Colorado benchmarkAcute mountain sickness affects 25% of all visitors sleeping above 2,450 m (8,000 ft) in Colorado.

The CDC also notes that fitness and training do not affect the risk, and that children are as susceptible as adults.

Elevation of Guatemala’s travel hubs

Town elevations are the digital elevation model value (SRTM3 or GTOPO30, as served by GeoNames) at each town’s point in the GeoNames gazetteer: an average over roughly a 90 m square (SRTM3) or a 900 m square (GTOPO30), rounded here to the nearest 10 m except below 10 m. A town centre on a slope spans tens of metres, so treat each as approximate.

PlaceElevation (m)Elevation (ft)Against the CDC 2,450 m sleeping line
Río Dulce~7~23Far below
Monterrico (Pacific)~10~33Far below
Flores~120~400Far below
Tikal~240~790Far below
Retalhuleu~240~790Far below
Lanquín~350~1,150Far below
Cobán~1,330~4,350Below
Guatemala City~1,510~4,950Below
Antigua Guatemala~1,580~5,190Below
Panajachel~1,580~5,190Below
San Marcos La Laguna~1,590~5,200Below
San Pedro La Laguna~1,590~5,220Below
Santiago Atitlán~1,600~5,260Below
San Juan La Laguna~1,610~5,270Below
Santa Cruz La Laguna~1,690~5,530Below
Huehuetenango~1,910~6,260Below
Nebaj~1,910~6,260Below
Sololá~2,040~6,710Below
Chichicastenango~2,080~6,810Below
Comalapa~2,120~6,940Below
Tecpán~2,290~7,520Just below
Quetzaltenango (Xela)~2,350~7,710Just below
Totonicapán~2,500~8,200At or just above
Todos Santos Cuchumatán~2,500~8,200At or just above

A reader flying into Guatemala City lands at about 1,510 m, already above the CDC’s 1,200 m “low altitude” starting point used in its one-day rule.

Volcano summits

Summit heights are the GeoNames “elevation” field for each volcano (the satellite dem value there is lower, because it averages the summit with the slopes around it), except Agua, where we use the Ministerio de Cultura y Deportes’ figure of 3,766 m; GeoNames gives 3,760 m.

VolcanoSummit (m)Summit (ft)Our guide
Pacaya2,5528,373Pacaya
San Pedro (Lake Atitlán)3,0209,908San Pedro volcano
Tolimán3,15810,361—
Atitlán3,53511,598—
Agua3,76612,356Volcán de Agua
Fuego3,76312,346Fuego status
Santa María (near Xela)3,77212,375Santa María
Acatenango3,97613,045Acatenango
Tajumulco4,22013,845Tajumulco

How the CDC lines apply:

  • Up and back in a day: the CDC says a day trip to high altitude with an evening return to a lower altitude is much less stressful on the body than sleeping high.
  • Sleeping on the mountain: our Acatenango and Tajumulco guides describe trips that camp on the mountain, below summits of 3,976 m and 4,220 m. Operators publish their own camp heights; we have not verified one, so ask yours and compare it with the 2,450 m and 2,750 m lines.
  • Staging. The CDC’s own example of a protective step is spending at least 2-3 nights at about 2,450-2,750 m before going higher. Antigua (about 1,580 m) and Xela (about 2,350 m) are both below that band.

Symptoms and what the CDC says to do

  • Symptoms (acute mountain sickness): the CDC says they are like those of an alcohol hangover, and that headache, the cardinal symptom, usually comes with one or more of loss of appetite, dizziness, fatigue, nausea or, occasionally, vomiting.
  • Timing: the CDC says onset is usually 2-12 hours after arriving at altitude or after climbing higher, often during or after the first night, and that it generally resolves within 12-48 hours if you do not climb higher.
  • Descent: improves rapidly with a descent of 300 m (1,000 ft) or more. If symptoms get worse at the same altitude despite treatment, the CDC says descent is mandatory.
  • Other hazards on the same summits: the UK Foreign Office warns that some Guatemalan volcanoes have freezing night temperatures and that there is no mountain rescue service; the US State Department advises hiking volcanoes only with a qualified local guide.

Sources

Contains GeoNames data (geonames.org), CC BY 4.0. This page is information, not medical advice. Information current as of 25 September 2026.

Frequently Asked Questions

Is Guatemala high altitude?

Parts of it. Guatemala City (about 1,510 m), Antigua (about 1,580 m) and the Lake Atitlán towns (about 1,580-1,690 m) are moderate altitude. Quetzaltenango (about 2,350 m), Totonicapán and Todos Santos Cuchumatán (about 2,500 m) are higher. Flores, Tikal, Lanquín, Río Dulce and the Pacific beaches are near sea level or low. The volcano summits run from Pacaya (2,552 m) to Tajumulco (4,220 m). Town figures are satellite elevation-model values at the GeoNames gazetteer point for each town.

Can you get altitude sickness in Antigua Guatemala?

Antigua sits at about 1,580 m, below the 2,450 m sleeping altitude at which the CDC Yellow Book says any unacclimatized traveller is at risk of altitude illness. The CDC adds that risk exists sometimes lower, so the line is a guide, not a guarantee. Antigua is the usual base for the Acatenango hike, which goes far higher.

Can you get altitude sickness on Acatenango?

Yes, it is possible. Acatenango’s summit is 3,976 m, and the trip described in our Acatenango guide camps overnight on the mountain. The CDC Yellow Book says anyone sleeping at 2,450 m or higher without acclimatization is at risk, that symptoms usually start 2 to 12 hours after arrival at altitude, and that descending 300 m or more improves acute mountain sickness. Ask your operator for the camp’s elevation.

What are the symptoms of altitude sickness?

According to the CDC Yellow Book, acute mountain sickness feels like an alcohol hangover: headache is the main symptom, usually with one or more of loss of appetite, dizziness, fatigue, nausea or, occasionally, vomiting. The CDC says onset is usually 2 to 12 hours after arriving at altitude, often during or after the first night. It improves rapidly with descent of 300 m (1,000 ft) or more.

Should I take altitude sickness pills for Guatemala?

That is a question for a doctor or travel clinic before you go. The CDC Yellow Book’s guidance on preventive medication is written for healthcare professionals and depends on the sleeping altitude and how fast you climb. We do not give dosing advice.